Anti-Aging & Longevity

SS-31

Name: SS-31 - Fraction Research
Availability: InStock

Price range: $59.99 through $143.99

Lot verification pending publication for this compound

Mitochondria-targeting aromatic-cationic tetrapeptide

CAS Number: 736992-21-5
Form: Lyophilized
Purity: ≥99% by HPLC-UV

Cold-Packed Protected seasonal packaging

Dispatches ≤48hr From Columbia, SC

Lot Verified COA included with every order

Independently Tested HPLC-UV verified, every single lot

Lot-traceable — matched to a public Certificate of Analysis

Research Use Only — not for human or veterinary use

View Certificate of Analysis

What You Receive

1× Research Vial

SS-31 — nominal content per selected size
Lyophilized
Tamper-evident seal
Lot-numbered label
Lot-matched Certificate of Analysis

Verification

Current Lot & Certificate of Analysis

Lot verification data for this compound hasn’t been published to the COA Library yet.

Browse the COA Library

Specifications

Technical Specifications

CAS Number 736992-21-5

Physical Form Lyophilized

Purity Specification ≥99% by HPLC-UV

Analytical Method HPLC-UV, 218nm

Research Context

Research Overview

SS-31, also known as Elamipretide or MTP-131, is a synthetic aromatic-cationic tetrapeptide with the sequence D-Arg-dimethylTyr-Lys-Phe-NH₂. CAS 736992-21-5, molecular weight approximately 638.78 g/mol. The compound belongs to the Szeto-Schiller (SS) family of mitochondria-targeting peptides developed by Hazel Szeto at Cornell University.

SS-31 is designed to selectively partition into the inner mitochondrial membrane (IMM) through electrostatic and hydrophobic interactions, where it binds to cardiolipin — a phospholipid unique to and critical for the structural integrity of the IMM. Research applications include studies of mitochondrial electron transport chain function, reactive oxygen species (ROS) production, cardiolipin peroxidation, mitochondrial membrane potential dynamics, and models of mitochondrial dysfunction associated with aging and cellular stress. SS-31 is one of the most widely studied compounds in the field of mitochondria-targeted therapeutics research.

Supplied as a lyophilized powder. Each lot is independently tested by HPLC-UV with a minimum purity threshold of ≥99.0%. Molecular identity confirmed by LC-MS prior to release. Certificate of Analysis available for every lot number.

For laboratory and in-vitro research use only. Not for human or veterinary use. Not FDA approved.

References

Peer-reviewed literature references for this compound are being compiled and will be published here.

Documentation

Technical Documentation

COA Certificate of Analysis View in COA Library TDS Technical Data Sheet PDF SDS Safety Data Sheet PDF

Fulfillment

Fulfillment & Packaging

Ships From

Columbia, South Carolina

Dispatch Timeframe

Within 48 hours of order confirmation

Cold-Chain Packaging

Insulated, seasonally adjusted packaging protects material in transit

Tamper-Evident Vial

Every vial ships sealed and lot-labeled

Shipping Area

Domestic (U.S.) shipping only

Shipping Cost

Calculated at checkout — see the Shipping Policy for full details

Questions

Frequently Asked Questions

Is this lot independently tested?

Yes. Every lot is tested by an independent third-party laboratory using HPLC-UV before it is released for sale, and results are published in the COA Library.

How do I locate my lot's Certificate of Analysis?

Use the "View Certificate of Analysis" link on this page, or search the COA Library directly by compound name or the lot number printed on your vial label.

What analytical methods are used?

Purity is determined by HPLC-UV. Molecular identity is confirmed by LC-MS prior to release.

How is the material packaged?

Material ships in a tamper-evident, lot-labeled vial inside cold-chain packaging appropriate for the season.

What does "Research Use Only" mean?

This product is sold exclusively for laboratory and in-vitro research applications by qualified researchers. It is not a drug, dietary supplement, or approved for human or veterinary use.