KPV is a synthetic tripeptide consisting of the amino acid sequence Lysine-Proline-Valine (K-P-V), representing the C-terminal tripeptide sequence of alpha-melanocyte-stimulating hormone (α-MSH). CAS 33008-07-0, molecular weight approximately 357.41 g/mol. The compound is supplied as the acetate salt form.
α-MSH and its terminal fragments have been studied extensively in the context of melanocortin receptor signaling, with particular interest in their roles in inflammatory pathway modulation. KPV has been investigated in cell culture systems for its interactions with the melanocortin-1 receptor (MC1R) and intracellular inflammatory mediators including NF-κB. Research applications include studies of melanocortin fragment pharmacology, cytokine regulation models, and gastrointestinal epithelial biology.
Supplied as a lyophilized powder. Each lot is independently tested by HPLC-UV with a minimum purity threshold of ≥99.0%. Molecular identity confirmed by LC-MS prior to release. Certificate of Analysis available for every lot number.
For laboratory and in-vitro research use only. Not for human or veterinary use. Not FDA approved.