Cognitive & Neuropeptides

Semax

Price range: $22.99 through $39.99

Lot verification pending publication for this compound

ACTH-derived neuropeptide analog

CAS Number: 80714-61-0
Molecular Formula: C₃₇H₅₁N₉O₁₀S
Molecular Weight: 813.95 g/mol
Form: Lyophilized
Purity: ≥99% by HPLC-UV

Cold-Packed Protected seasonal packaging

Dispatches ≤48hr From Columbia, SC

Lot Verified COA included with every order

Independently Tested HPLC-UV verified, every single lot

Lot-traceable — matched to a public Certificate of Analysis

Research Use Only — not for human or veterinary use

View Certificate of Analysis

What You Receive

1× Research Vial

Semax — nominal content per selected size
Lyophilized
Tamper-evident seal
Lot-numbered label
Lot-matched Certificate of Analysis

Verification

Current Lot & Certificate of Analysis

Lot verification data for this compound hasn’t been published to the COA Library yet.

Browse the COA Library

Specifications

Technical Specifications

CAS Number 80714-61-0

Molecular Formula C₃₇H₅₁N₉O₁₀S

Molecular Weight 813.95 g/mol

Physical Form Lyophilized

Purity Specification ≥99% by HPLC-UV

Analytical Method HPLC-UV, 218nm

Research Context

Research Overview

Semax is a synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-7), with the sequence Met-Glu-His-Phe-Pro-Gly-Pro and a Pro-Gly-Pro C-terminal extension designed to improve metabolic stability. CAS 80714-61-0, molecular formula C₃₇H₅₁N₉O₁₀S, molecular weight 813.95 g/mol.

Originally developed at the Institute of Molecular Genetics in Moscow, Semax has been studied in the context of central nervous system research, including investigations into BDNF and NGF expression regulation, neuroprotection models, and dopaminergic system modulation. Research has examined its pharmacological interactions with ACTH receptors and its effects in ischemia and oxidative stress cell culture models. It represents a well-characterized tool compound for studying ACTH-derived peptide pharmacology and neurotrophin regulation in vitro.

Supplied as a lyophilized powder. Each lot is independently tested by HPLC-UV at 218nm with a minimum purity threshold of ≥99.0%. Molecular identity confirmed by LC-MS prior to release. Certificate of Analysis available for every lot number.

For laboratory and in-vitro research use only. Not for human or veterinary use. Not FDA approved.

References

Peer-reviewed literature references for this compound are being compiled and will be published here.

Documentation

Technical Documentation

COA Certificate of Analysis View in COA Library TDS Technical Data Sheet PDF SDS Safety Data Sheet PDF

Fulfillment

Fulfillment & Packaging

Ships From

Columbia, South Carolina

Dispatch Timeframe

Within 48 hours of order confirmation

Cold-Chain Packaging

Insulated, seasonally adjusted packaging protects material in transit

Tamper-Evident Vial

Every vial ships sealed and lot-labeled

Shipping Area

Domestic (U.S.) shipping only

Shipping Cost

Calculated at checkout — see the Shipping Policy for full details

Questions

Frequently Asked Questions

Is this lot independently tested?

Yes. Every lot is tested by an independent third-party laboratory using HPLC-UV before it is released for sale, and results are published in the COA Library.

How do I locate my lot's Certificate of Analysis?

Use the "View Certificate of Analysis" link on this page, or search the COA Library directly by compound name or the lot number printed on your vial label.

What analytical methods are used?

Purity is determined by HPLC-UV. Molecular identity is confirmed by LC-MS prior to release.

How is the material packaged?

Material ships in a tamper-evident, lot-labeled vial inside cold-chain packaging appropriate for the season.

What does "Research Use Only" mean?

This product is sold exclusively for laboratory and in-vitro research applications by qualified researchers. It is not a drug, dietary supplement, or approved for human or veterinary use.