PT-141, also known as Bremelanotide, is a synthetic cyclic heptapeptide melanocortin receptor agonist. CAS 189691-06-3, molecular formula C₅₀H₆₈N₁₄O₁₀, molecular weight 1025.19 g/mol. It is structurally derived from Melanotan II (MT-II) and acts as a non-selective agonist at melanocortin receptors MC1R, MC3R, MC4R, and MC5R.
Research interest in PT-141 has focused primarily on its central nervous system activity via MC3R and MC4R, which are expressed in hypothalamic and limbic regions associated with autonomic and neuroendocrine regulation. It has been studied in models of melanocortin signaling, reproductive neuroendocrinology, and hypothalamic circuit function. Note: Bremelanotide (Vyleesi) has received FDA approval for a specific clinical indication; this compound is supplied strictly for non-clinical laboratory research purposes.
Supplied as a lyophilized powder. Each lot is independently tested by HPLC-UV with a minimum purity threshold of ≥99.0%. Molecular identity confirmed by LC-MS prior to release. Certificate of Analysis available for every lot number.
For laboratory and in-vitro research use only. Not for human or veterinary use. Not FDA approved.